Sex differences in hallmarks of Alzheimer’s disease: new study finds faster tau accumulation in female brains

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Contributed by Ashley A. Keiser, PhD A new study from researchers in Sweden published in Brain finds faster accumulation of a major hallmark of Alzheimer’s disease, neurofibrillary protein aggregates containing tau in female, compared with male brains. Researchers also found greater memory impairments in women with Alzheimer’s disease. Sex differences in Alzheimer’s disease risk have been extensively reported. Particularly, women exhibit greater cognitive impairment and the rate of acceleration of impairment is observed to exceed men. Women are also twice as likely to be diagnosed with Alzheimer’s disease. Although previous cross-sectional studies that capture a single data point in time…

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MIND Matters | Quarterly Newsletter | Winter 2021

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Message from the Director Happy New Year, Friends of UCI MIND! For many of us, a New Year brings the promise of fresh starts and new beginnings. In 2021, it also means a welcomed good-bye to a very long 2020. Despite the challenges that 2020 brought, it also brought progress that must now continue in 2021. This includes progress in social justice, progress in fighting the COVID-19 pandemic, and progress in research to rid the world of Alzheimer’s disease and related dementias. UCI MIND is committed to contributing to further progress in each of these areas. Though the COVID-19 pandemic…

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Great Minds donate a lot

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UC Irvine’s Institute for Memory Impairments and Neurological Disorders raised some $300,000 at its A December to Remember Gala on Dec. 5, 2020. The event took place virtually for the very first time, reaching over 850 viewers on multiple online channels including Facebook, Youtube and the UCI MIND website. A recording of the event is available to view on UCI MIND’s YouTube page. The online broadcast, co-hosted by UCI MIND Director Joshua Grill and auctioneer Zack Krone, included performances from Justin Willman, the star and creator of the hit Netflix series “Magic for Humans,” and Ashley Campbell, singer-songwriter and daughter of…

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