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UCI MIND faculty member Dr. Tahseen Mozaffar awarded $4.2M grant to study rare muscle disorder affecting aging Americans

Por Deslizador de carrusel, Comentario, En las noticias, MENTE UCI

UCI School of Medicine Tahseen Mozaffar, MD, a professor of neurology and director of the Division of Neuromuscular Disorders and the UCI-MDA ALS and Neuromuscular Center at UCI’s School of Medicine will lead a study on sporadic inclusion body myositis (sIBM), which affects aging adults causing asymmetric muscle weakness and severe disability. Currently untreatable, sporadic inclusion body myositis (sIBM) causes muscle weakness and severe disability Irvine, CA – April 6, 2021 – The National Institute of Arthritis and Musculoskeletal and Skin Diseases has awarded UCI a 5-year, $4.2 million grant to study sporadic inclusion body myositis (sIBM), which affects aging adults…

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Tracking the Alzheimer’s-Down syndrome connection

Por Deslizador de carrusel, Comentario, En las noticias, MENTE UCI

By the time they’re 40, most people with Down syndrome develop beta amyloid plaques in the brain — a key characteristic of Alzheimer’s disease. Scientists believe this is because they have an extra copy of chromosome 21, which carries an amyloid-producing gene. Many people with Down syndrome do develop Alzheimer’s disease, but some manage to avoid the devastating neurodegenerative consequences despite having these plaques in their brains. To learn more about the connection between Down syndrome and Alzheimer’s disease, UCI School of Medicine researchers are spearheading a major international research effort that will follow hundreds of adults with the syndrome…

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Why more of us are living to 100

Por Deslizador de carrusel, Comentario, En las noticias, MENTE UCI

On Monday, MPR News host Kerri Miller talked to two researchers, including UCI MIND investigator Claudia Kawas, MD, about what they’re learning about living to be 100. Do you have to win the genetic lottery to live an entire century? Or could research unlock the secret to living longer and living longer well? Listen here >

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Leslie Thompson Tackles Huntington’s Disease One Gene at a Time

Por Deslizador de carrusel, Comentario, En las noticias, MENTE UCI

The UCI professor has dedicated her career to finding answers to a rare genetic disease’s most crucial questions. An estimated 30,000 genes make up the human genome, with an individual’s entire uniqueness created by genetic mutations. From tissues and blood as well as distinctive physical features, like eye and hair color to temperament and so much more, genes are the coded instructions for building an entire person. But sometimes those instructions contain errors and genes can mutate to form many different things, including diseases. One such disease, Huntington’s disease, is a rare, inherited disease triggered by a single genetic mutation…

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Great Minds donate a lot

Por Deslizador de carrusel, Comentario, Eventos comunitarios, En las noticias, MENTE UCI

UC Irvine’s Institute for Memory Impairments and Neurological Disorders raised some $300,000 at its A December to Remember Gala on Dec. 5, 2020. The event took place virtually for the very first time, reaching over 850 viewers on multiple online channels including Facebook, Youtube and the UCI MIND website. A recording of the event is available to view on UCI MIND’s YouTube page. The online broadcast, co-hosted by UCI MIND Director Joshua Grill and auctioneer Zack Krone, included performances from Justin Willman, the star and creator of the hit Netflix series “Magic for Humans,” and Ashley Campbell, singer-songwriter and daughter of…

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4 questions to ask yourself about living to 100 — because there’s a chance you will

Por Deslizador de carrusel, En las noticias, MENTE UCI

MarketWatch – Nov. 30, 2020 The University of California, Irvine’s Institute for Memory Impairments and Neurological Disorders (UCI MIND) has studied elderly individuals as part of its “90+ Study” since 2003, analyzing the ways in which nearly 2,000 participants go about their lives in their 90s and 100s, as well as what may have contributed to that longevity and underlying cognitive disabilities they may or may not know they have. … Half of children born this decade can expect to see their 103rd or 104th birthday, Claudia Kawas, co-principal investigator of The 90+ Study, told CBS. Read more >

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UCI Spearheads $109M Down Syndrome, Alzheimer’s Study

Por Deslizador de carrusel, Comentario, En las noticias, MENTE UCI

The University of California, Irvine is undertaking a five-year, multi-million dollar project to expand research on Alzheimer’s disease in people with Down syndrome. The National Institute of Health awarded a $109 million grant to the Alzheimer’s Biomarkers Consortium-Down Syndrome in late October. The international team, led by UCI principal investigators Elizabeth Head and Mark Mapstone, aims to identify biomarkers that indicate the progression of Alzheimer’s disease in adults with Down syndrome. Subscribers to the Orange County Business Journal can read more here >          

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