Carousel Slider

The University of California, Irvine is undertaking a five-year, multi-million dollar project to expand research on Alzheimer’s disease in people with Down syndrome. The National Institute of Health awarded a $109 million grant to the Alzheimer’s Biomarkers Consortium-Down Syndrome in late October. The international team, led by UCI principal investigators Elizabeth Head and Mark Mapstone, aims to identify biomarkers that indicate the progression of Alzheimer’s disease in adults with Down syndrome. Subscribers to the Orange County Business Journal can read more here >          

The post UCI Spearheads $109M Down Syndrome, Alzheimer’s Study appeared first on UCI MIND.

Will Biogen’s aducanumab become the first drug approved to slow progression of Alzheimer’s disease? UCI MIND faculty member and chair of UCI Statistics, Dr. Daniel Gillen, and other experts comment on ALZFORUM.
The post Aducanumab Still Needs to Prove …

The post New insights from study of people age 90 and above appeared first on UCI MIND.

Contributed by UCI News: UCI’s Center for Neural Circuit Mapping is redrawing our understanding of mechanisms underlying several common disorders by Ian Anzlowar, UCI | November 18, 2020 Thanks to Xiangmin Xu and his team at the UCI School of Medicine’s Center for Neural Circuit Mapping, lazy eye, Alzheimer’s and other neurological diseases could become a thing of the past. Opened earlier this year, the unit focuses on basic neuroscience research, advancing knowledge of the brain by defining mechanisms and pathways that underlie neurodevelopmental, neuropsychiatric and neurodegenerative disorders. “Our 30 to 40 investigators can join forces to tackle large-scale research…

The post Cartographers of the brain appeared first on UCI MIND.

“Our findings suggest that older individuals experiencing cognitive decline have relatively stable ideological preferences, but these preferences lose their connection to political policy details. Future studies conducted during an election year ma…

FLASH radiation therapy, also called FLASH-RT, can eliminate the debilitating side effects associated with traditional radiation therapy by delivering the same dose in tenths of seconds, and can remove tumors, according to a study published in Clinical Cancer Research. … Charles Limoli, PhD, a researcher and professor of radiation oncology at University of California Irvine [said] It’s not unreasonable to expect that in 10 years, this may become a widespread option for radiotherapy patients worldwide.”

The post FLASH radiation therapy can help treat cancer without neurocognitive side effects, study finds appeared first on UCI MIND.

Congratulations to UCI MIND investigators, Drs. Elizabeth Head and Mark Mapstone, on earning a 5-year $100 million grant to study biomarkers for Alzheimer’s disease in people with Down syndrome. The  Alzheimer’s Biomarker Consortium – Down Syndrome (ABC-DS) evolved from the longstanding contributions of Dr. Ira Lott and Eric Doran who had the insight to include older people with Down syndrome in Alzheimer’s disease research.  People with Down syndrome are at very high risk for Alzheimer disease as their extra copy of chromosome 21 leads to accelerated amyloid buildup with aging. The new grant will help researchers improve understanding of the unique disease progression…

The post NIH Awards Over $100 Million to Examine Biomarkers of Alzheimer’s Disease in Adults with Down Syndrome appeared first on UCI MIND.