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UCI Spearheads $109M Down Syndrome, Alzheimer’s Study

By Carousel Slider, Commentary, In the News, UCI MIND

The University of California, Irvine is undertaking a five-year, multi-million dollar project to expand research on Alzheimer’s disease in people with Down syndrome. The National Institute of Health awarded a $109 million grant to the Alzheimer’s Biomarkers Consortium-Down Syndrome in late October. The international team, led by UCI principal investigators Elizabeth Head and Mark Mapstone, aims to identify biomarkers that indicate the progression of Alzheimer’s disease in adults with Down syndrome. Subscribers to the Orange County Business Journal can read more here >          

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Cartographers of the brain

By Carousel Slider, Commentary, In the News, UCI MIND

Contributed by UCI News: UCI’s Center for Neural Circuit Mapping is redrawing our understanding of mechanisms underlying several common disorders by Ian Anzlowar, UCI | November 18, 2020 Thanks to Xiangmin Xu and his team at the UCI School of Medicine’s Center for Neural Circuit Mapping, lazy eye, Alzheimer’s and other neurological diseases could become a thing of the past. Opened earlier this year, the unit focuses on basic neuroscience research, advancing knowledge of the brain by defining mechanisms and pathways that underlie neurodevelopmental, neuropsychiatric and neurodegenerative disorders. “Our 30 to 40 investigators can join forces to tackle large-scale research…

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UCI MIND adapts annual fundraiser for Alzheimer’s research with virtual venue

By Carousel Slider, Community Events, In the News, UCI MIND

For the first time in the event’s decade-long history, the University of California, Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND)’s A December to Remember gala will raise awareness and funds for Alzheimer’s research in a digital setting. While many sectors remain at a standstill due to the pandemic, nonprofits like UCI MIND know that their mission must march forward. The virtual gala event will take place online on Saturday, Dec. 5 from 5:30-7 p.m., and is free to attend. To register to attend, visit https://aesbid.co/ELP/UCIMIND20/. “We saw an incredible opportunity as we reimagined our annual gala to…

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FLASH radiation therapy can help treat cancer without neurocognitive side effects, study finds

By Carousel Slider, Commentary, In the News, UCI MIND

FLASH radiation therapy, also called FLASH-RT, can eliminate the debilitating side effects associated with traditional radiation therapy by delivering the same dose in tenths of seconds, and can remove tumors, according to a study published in Clinical Cancer Research. … Charles Limoli, PhD, a researcher and professor of radiation oncology at University of California Irvine [said] It’s not unreasonable to expect that in 10 years, this may become a widespread option for radiotherapy patients worldwide.”

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UCI MIND, UCSF, UC Davis, NAPCA, ICAN Launch Research Registry for Asian Americans and Pacific Islanders

By Carousel Slider, Commentary, Community Events, In the News, UCI MIND

UC San Francisco, UC Davis, UC Irvine, National Asian Pacific Center on Aging (NAPCA), International Children Assistance Network (ICAN) in partnership with over twenty community partners serving diverse Asian Americans and Pacific Islanders (AAPI) communities in California and nationwide, is pleased to announce the launch of the Collaborative Approach for AAPI Research and Education (CARE) research registry. The CARE registry team reflect multiple diverse AAPI cultures and languages. CARE is an opportunity for AAPI to participate in important research that may affect ourselves, our parents, children and grandchildren. Some of the important research may contribute to finding cures for and/or ways to…

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NIH Awards Over $100 Million to Examine Biomarkers of Alzheimer’s Disease in Adults with Down Syndrome

By Carousel Slider, Commentary, In the News, UCI MIND

Congratulations to UCI MIND investigators, Drs. Elizabeth Head and Mark Mapstone, on earning a 5-year $100 million grant to study biomarkers for Alzheimer’s disease in people with Down syndrome. The  Alzheimer’s Biomarker Consortium – Down Syndrome (ABC-DS) evolved from the longstanding contributions of Dr. Ira Lott and Eric Doran who had the insight to include older people with Down syndrome in Alzheimer’s disease research.  People with Down syndrome are at very high risk for Alzheimer disease as their extra copy of chromosome 21 leads to accelerated amyloid buildup with aging. The new grant will help researchers improve understanding of the unique disease progression…

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Dr. Joshua Grill discusses Alzheimer’s clinical trials during the pandemic with NPR

By Carousel Slider, Commentary, COVID-19, In the News, UCI MIND

(3-minute listen) After cases began emerging worldwide, thousands of clinical trials unrelated to COVID-19 were paused or canceled amid fears that participants would be infected. But now, some researchers are finding ways to carry on in spite of the coronavirus. “It’s been a struggle of course,” says Joshua Grill, who directs the Institute for Memory Impairments and Neurological Disorders at the University of California, Irvine. “But I think there’s an imperative for us to find ways to move forward.”

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