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Sex differences in hallmarks of Alzheimer’s disease: new study finds faster tau accumulation in female brains

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Contributed by Ashley A. Keiser, PhD A new study from researchers in Sweden published in Brain finds faster accumulation of a major hallmark of Alzheimer’s disease, neurofibrillary protein aggregates containing tau in female, compared with male brains. Researchers also found greater memory impairments in women with Alzheimer’s disease. Sex differences in Alzheimer’s disease risk have been extensively reported. Particularly, women exhibit greater cognitive impairment and the rate of acceleration of impairment is observed to exceed men. Women are also twice as likely to be diagnosed with Alzheimer’s disease. Although previous cross-sectional studies that capture a single data point in time…

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UCI MIND faculty member Dr. Tahseen Mozaffar awarded $4.2M grant to study rare muscle disorder affecting aging Americans

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UCI School of Medicine Tahseen Mozaffar, MD, a professor of neurology and director of the Division of Neuromuscular Disorders and the UCI-MDA ALS and Neuromuscular Center at UCI’s School of Medicine will lead a study on sporadic inclusion body myositis (sIBM), which affects aging adults causing asymmetric muscle weakness and severe disability. Currently untreatable, sporadic inclusion body myositis (sIBM) causes muscle weakness and severe disability Irvine, CA – April 6, 2021 – The National Institute of Arthritis and Musculoskeletal and Skin Diseases has awarded UCI a 5-year, $4.2 million grant to study sporadic inclusion body myositis (sIBM), which affects aging adults…

帖子 UCI MIND faculty member Dr. Tahseen Mozaffar awarded $4.2M grant to study rare muscle disorder affecting aging Americans 首先出现 UCI思想.

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Tracking the Alzheimer’s-Down syndrome connection

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By the time they’re 40, most people with Down syndrome develop beta amyloid plaques in the brain — a key characteristic of Alzheimer’s disease. Scientists believe this is because they have an extra copy of chromosome 21, which carries an amyloid-producing gene. Many people with Down syndrome do develop Alzheimer’s disease, but some manage to avoid the devastating neurodegenerative consequences despite having these plaques in their brains. To learn more about the connection between Down syndrome and Alzheimer’s disease, UCI School of Medicine researchers are spearheading a major international research effort that will follow hundreds of adults with the syndrome…

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Why more of us are living to 100

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On Monday, MPR News host Kerri Miller talked to two researchers, including UCI MIND investigator Claudia Kawas, MD, about what they’re learning about living to be 100. Do you have to win the genetic lottery to live an entire century? Or could research unlock the secret to living longer and living longer well? Listen here >

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Additional Vaccination Information

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Contributed by Orange County Aging Services Collaborative It is important that our most vulnerable community members have access to COVID-19 vaccination appointments.  The Abrazar team can assist clients with scheduling an appointment.  If needed, transportation can also be scheduled.  Please note that the age eligibility is now 50+ (see below for other eligible community members).   VACCINATION APPOINTMENTS & ADDITIONAL INFORMATION: Call Abrazar’s COVID-19 Vaccination Call Center at (714) 278-4670. All questions can be sent to covidinfo@abrazarinc.com Call Center Team Members are bilingual and speak English, Spanish and Vietnamese. Referrals for other languages can be made. Case managers and family members can call…

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Carol Choi Named District 74 Woman of Distinction

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UC Irvine’s very own Carol Choi has been named among the 74th Assembly District 2021 Women of Distinction by Assemblywoman Cottie Petrie-Norris. The annual recognition occurs each March in honor of Women’s History Month to recognize women “who have shown extraordinary work, mentorship and leadership.” For those who are privileged to know and work with Carol Choi, this honor comes as no surprise. Carol embodies leadership through service on several committees at UC Irvine, including as a University Trustee. Additionally, Carol serves as Board Chair of the Korean American Alumni Chapter of the Alumni Association whose Founding President, Alexander Kim,…

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