Irvine, Calif. – UCI Health and UCI Alpha Clinic have launched the first and only U.S. clinical trial to test the safety and tolerability of IMM01-STEM in patients with muscle atrophy related to knee osteoarthritis.
Up to 18 patients ranging in …
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The actor Chris Hemsworth recently publicly disclosed that he learned that he carries two copies of the Alzheimer’s disease risk gene Apolipoprotein (APOE) e4 (https://www.goodmorningamerica.com/culture/story/chris-hemsworth-discovers-risk-alzheimers-disease-series-limitless-93442609). We’ve previously discussed direct-to-consumer genetic testing that includes the option for APOE testing on the UCI MIND blog (https://mind.uci.edu/fda-approves-23andme-limited-direct-consumer-genetic-risk-testing/). APOE is the strongest known genetic risk factor for Alzheimer’s disease. People who carry one or two copies of the e4 allele are at increased risk for Alzheimer’s disease, while people who carry the e2 allele are at lower risk (most people carry two copies of the e3 allele). But people with e4 don’t always develop…
The post Learning Alzheimer’s Risk appeared first on UCI MIND.
Healthline – “There is a lot of evidence that links sleep apnea to Alzheimer’s disease risk,” added Bryce Mander, Ph.D, assistant professor, Psychiatry & Human Behavior, School of Medicine at the University of California, Irvine. “But there i…
UCI MIND Director Joshua Grill, PhD and Jason Karlawish, PhD, Co-Director of the Penn Memory Center were featured in a recent podcast episode for the Wisconsin Alzheimer’s Disease Research Center: The Case for Disclosing Biomarker Results to Al…
Orange, Calif., – UCI Health received its 17th consecutive ‘A’ in the fall 2022 Leapfrog Hospital Safety Grade. This national distinction, which recognizes a health system’s commitment to patient safety and achievements in preventing harm, …
Orange, Calif., – UCI Health received its 17th consecutive “A” in the fall 2022 Leapfrog Hospital Safety Grade. This national distinction, which recognizes a health system’s commitment to patient safety and achievements in preve…
Contributed by Joshua Grill, PhD On November 14, Roche announced negative topline results for their GRADUATE program testing gantenerumab, a monoclonal antibody against the beta amyloid protein that accumulates in the brain of people with Alzheimer’s disease. The program included two phase 3 trials (GRADUATE 1 and GRADUATE 2). As with other recent trials, the studies included patients with “early Alzheimer’s disease,” including people with Mild Cognitive Impairment and mild dementia. The trials were large and lengthy, with 1965 participants (across the two studies) who were followed for 27 months. According to the press release, participants randomized to gantenerumab demonstrated…
The post Topline results announced for Phase 3 trial of gantenerumab appeared first on UCI MIND.
Orange, Calif. — UCI Health and General Catalyst have formed a multiyear collaboration to advance digital transformation that increases the efficiency of healthcare delivery, expands health equity and creates new care models that meet the changin…
Irvine, Calif. — More than 3,000 participants, donors and supporters who joined the 2022 UCI Anti-Cancer Challenge on Oct. 8 helped raise $1 million for innovative cancer research.
All proceeds will support promising cancer pilot projects and ear…
Find out in this infographic from the National Institute on Aging: https://go.usa.gov/xtEmu
The post If a family member has Alzheimer’s disease, will I have it, too? appeared first on UCI MIND.
“Researchers are working hard to find a cure to Alzheimer’s disease … Through their efforts, new research and studies have proven helpful in ways to prevent the disease and even possible treatments. We learn about these findings from our pa…
Irvine, Calif. — UCI Health and the UCI Alpha Clinic are conducting a clinical trial of an investigational cell therapy in patients with generalized myasthenia gravis, a rare autoimmune disorder.
The therapy, called Descartes-08, is an mRNA-modif…
Irvine, Calif. — UCI Health and the UCI Alpha Clinic are conducting a clinical trial of an investigational cell therapy in patients with generalized myasthenia gravis, a rare autoimmune disorder.
The therapy, called Descartes-08, is an mRNA-modif…
Orange, Calif. — The American College of Surgeons’ National Surgical Quality Improvement Program (NSQIP®) has again recognized UCI Medical Center as one of 78 participating hospitals to achieve meritorious outcomes for surgical patient …
Irvine, Calif. — UCI Health and the UCI Alpha Clinic have opened the first clinical trial to assess the safety and effectiveness of CYNK-001, a natural killer cell therapy, in patients with recurrent glioblastoma (GBM), the deadliest form of brai…
IN THE NEWS: An $8 million grant and designation as one of the state’s network of stem cell therapy clinics is enabling UC Irvine to expand patient access to gene and stem cell clinical trials, clinic director Dr. Daniela Bota tells KFI-AM 640 radio.
O…
Eat This, Not That! – Nov. 1, 2022 ‘An increase in dementia cases is alarming, especially since there’s no cure and Dr. Michael Yassa, neurobiologist and director of the Center for the Neurobiology of Learning and Memory at the University of California, Irvine shares why there’s an uptick. “Remember that the biggest risk factor is age, and we are an aging population. Advances in medical care have managed to extend our lifespan beyond anything we could have ever imagined a hundred or two hundred years ago. So the prevalence of dementia is increasing because we have more and more people…
The post The #1 Thing You Can Do to Lower Your Dementia Risk appeared first on UCI MIND.
IN THE NEWS: A UCI Health pediatric infectious disease expert describes research underway on a vaccine for respiratory syncytial virus (RSV), a common respiratory virus little seen during the pandemic that is sending severely ill young children to hosp…
IN THE NEWS: A UCI Health pediatric infectious disease expert describes research underway on a vaccine for respiratory syncytial virus (RSV), a common respiratory virus little seen during the pandemic that is sending severely ill young children to hosp…
IN THE NEWS: Respiratory syncytial virus (RSV) is a common respiratory virus that causes mild, cold-like symptoms but can require hospitalization in children under 12 months of age.
Recently, there has been a rise of RSV cases in small child which has…