News

Sex differences in hallmarks of Alzheimer’s disease: new study finds faster tau accumulation in female brains

By Commentary, Community Events, In the News, UCI MIND

Contributed by Ashley A. Keiser, PhD A new study from researchers in Sweden published in Brain finds faster accumulation of a major hallmark of Alzheimer’s disease, neurofibrillary protein aggregates containing tau in female, compared with male brains. Researchers also found greater memory impairments in women with Alzheimer’s disease. Sex differences in Alzheimer’s disease risk have been extensively reported. Particularly, women exhibit greater cognitive impairment and the rate of acceleration of impairment is observed to exceed men. Women are also twice as likely to be diagnosed with Alzheimer’s disease. Although previous cross-sectional studies that capture a single data point in time…

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UCI MIND faculty member Dr. Tahseen Mozaffar awarded $4.2M grant to study rare muscle disorder affecting aging Americans

By Carousel Slider, Commentary, In the News, UCI MIND

UCI School of Medicine Tahseen Mozaffar, MD, a professor of neurology and director of the Division of Neuromuscular Disorders and the UCI-MDA ALS and Neuromuscular Center at UCI’s School of Medicine will lead a study on sporadic inclusion body myositis (sIBM), which affects aging adults causing asymmetric muscle weakness and severe disability. Currently untreatable, sporadic inclusion body myositis (sIBM) causes muscle weakness and severe disability Irvine, CA – April 6, 2021 – The National Institute of Arthritis and Musculoskeletal and Skin Diseases has awarded UCI a 5-year, $4.2 million grant to study sporadic inclusion body myositis (sIBM), which affects aging adults…

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Tracking the Alzheimer’s-Down syndrome connection

By Carousel Slider, Commentary, In the News, UCI MIND

By the time they’re 40, most people with Down syndrome develop beta amyloid plaques in the brain — a key characteristic of Alzheimer’s disease. Scientists believe this is because they have an extra copy of chromosome 21, which carries an amyloid-producing gene. Many people with Down syndrome do develop Alzheimer’s disease, but some manage to avoid the devastating neurodegenerative consequences despite having these plaques in their brains. To learn more about the connection between Down syndrome and Alzheimer’s disease, UCI School of Medicine researchers are spearheading a major international research effort that will follow hundreds of adults with the syndrome…

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Why more of us are living to 100

By Carousel Slider, Commentary, In the News, UCI MIND

On Monday, MPR News host Kerri Miller talked to two researchers, including UCI MIND investigator Claudia Kawas, MD, about what they’re learning about living to be 100. Do you have to win the genetic lottery to live an entire century? Or could research unlock the secret to living longer and living longer well? Listen here >

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Additional Vaccination Information

By Commentary, COVID-19, In the News, UCI MIND

Contributed by Orange County Aging Services Collaborative It is important that our most vulnerable community members have access to COVID-19 vaccination appointments.  The Abrazar team can assist clients with scheduling an appointment.  If needed, transportation can also be scheduled.  Please note that the age eligibility is now 50+ (see below for other eligible community members).   VACCINATION APPOINTMENTS & ADDITIONAL INFORMATION: Call Abrazar’s COVID-19 Vaccination Call Center at (714) 278-4670. All questions can be sent to covidinfo@abrazarinc.com Call Center Team Members are bilingual and speak English, Spanish and Vietnamese. Referrals for other languages can be made. Case managers and family members can call…

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Carol Choi Named District 74 Woman of Distinction

By Commentary, In the News, UCI MIND

UC Irvine’s very own Carol Choi has been named among the 74th Assembly District 2021 Women of Distinction by Assemblywoman Cottie Petrie-Norris. The annual recognition occurs each March in honor of Women’s History Month to recognize women “who have shown extraordinary work, mentorship and leadership.” For those who are privileged to know and work with Carol Choi, this honor comes as no surprise. Carol embodies leadership through service on several committees at UC Irvine, including as a University Trustee. Additionally, Carol serves as Board Chair of the Korean American Alumni Chapter of the Alumni Association whose Founding President, Alexander Kim,…

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Introducing the new Alzheimers.gov!

By Commentary, UCI MIND

Contributed by the National Institute on Aging: NIA is pleased to announce Alzheimers.gov, a new website designed to educate and support people whose lives are touched by Alzheimer’s disease and related dementias. The website serves as the federal government portal for dementia information and resources. To develop Alzheimers.gov, we collaborated with people living with dementia, caregivers, advocates, researchers, and others to ensure an informative, easy-to-use, and empowering website. We are delighted to share it with you. Whether you are living with dementia, a family member or friend, health care professional, researcher, or advocate, Alzheimers.gov is designed for you. Explore the…

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World Down Syndrome Day 2021

By Commentary, UCI MIND

Yesterday, March 21st, was World Down Syndrome Day, a dedicated day to advocate for the rights of people with Down syndrome. Did you know that people with Down syndrome are at significantly increased risk to develop Alzheimer’s dementia? In this video clip, Paula Gann, mother of a daughter with Down syndrome and member of the California Governor’s Task Force on Alzheimer’s Prevention & Preparedness, shares how she and her daughter Kyle are working with UCI MIND researchers to advance knowledge, treatment, and care for people with Down syndrome and Alzheimer’s disease. To learn more about Down syndrome research at UCI…

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Leslie Thompson Tackles Huntington’s Disease One Gene at a Time

By Carousel Slider, Commentary, In the News, UCI MIND

The UCI professor has dedicated her career to finding answers to a rare genetic disease’s most crucial questions. An estimated 30,000 genes make up the human genome, with an individual’s entire uniqueness created by genetic mutations. From tissues and blood as well as distinctive physical features, like eye and hair color to temperament and so much more, genes are the coded instructions for building an entire person. But sometimes those instructions contain errors and genes can mutate to form many different things, including diseases. One such disease, Huntington’s disease, is a rare, inherited disease triggered by a single genetic mutation…

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