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Oct 23
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UCI MIND, UCSF, UC Davis, NAPCA, ICAN Launch Research Registry for Asian Americans and Pacific Islanders

By Carousel Slider, Commentary, Community Events, In the News, UCI MIND

UC San Francisco, UC Davis, UC Irvine, National Asian Pacific Center on Aging (NAPCA), International Children Assistance Network (ICAN) in partnership with over twenty community partners serving diverse Asian Americans and Pacific Islanders (AAPI) communities in California and nationwide, is pleased to announce the launch of the Collaborative Approach for AAPI Research and Education (CARE) research registry. The CARE registry team reflect multiple diverse AAPI cultures and languages. CARE is an opportunity for AAPI to participate in important research that may affect ourselves, our parents, children and grandchildren. Some of the important research may contribute to finding cures for and/or ways to…

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Oct 23
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NIH Awards Over $100 Million to Examine Biomarkers of Alzheimer’s Disease in Adults with Down Syndrome

By Carousel Slider, Commentary, In the News, UCI MIND

Congratulations to UCI MIND investigators, Drs. Elizabeth Head and Mark Mapstone, on earning a 5-year $100 million grant to study biomarkers for Alzheimer’s disease in people with Down syndrome. The  Alzheimer’s Biomarker Consortium – Down Syndrome (ABC-DS) evolved from the longstanding contributions of Dr. Ira Lott and Eric Doran who had the insight to include older people with Down syndrome in Alzheimer’s disease research.  People with Down syndrome are at very high risk for Alzheimer disease as their extra copy of chromosome 21 leads to accelerated amyloid buildup with aging. The new grant will help researchers improve understanding of the unique disease progression…

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Oct 20
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Today is #ResearchDiversity Day! Follow the Conversation on Twitter

By Commentary, Community Events, UCI MIND

Contributed by Franklin Garcia, PhD, UCI MIND Postdoctoral Fellow   “On this Research Diversity Day, I would like to share my early undergraduate experience that paved the way for my interest in aging research. The concept of pursuing a career in scientific research was new to me since, as a first-generation university student, I didn’t have mentors or older peers that could shed some insight or guidance. Fortunately, during my last two years as an undergraduate student at UC Irvine, I received mentorship from my research advisor, Prof. Frank LaFerla and the faculty advisors in the Neurobiology major. As an…

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Oct 20
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Dr. Joshua Grill discusses Alzheimer’s clinical trials during the pandemic with NPR

By Carousel Slider, Commentary, COVID-19, In the News, UCI MIND

(3-minute listen) After cases began emerging worldwide, thousands of clinical trials unrelated to COVID-19 were paused or canceled amid fears that participants would be infected. But now, some researchers are finding ways to carry on in spite of the coronavirus. “It’s been a struggle of course,” says Joshua Grill, who directs the Institute for Memory Impairments and Neurological Disorders at the University of California, Irvine. “But I think there’s an imperative for us to find ways to move forward.”

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Oct 19
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Maria Shriver named Variety’s Entertainment Philanthropist of the Year

By Commentary, In the News, UCI MIND

Congratulations to Maria Shriver for being selected as Variety’s Entertainment Philanthropist of the Year for her trailblazing Alzheimer’s advocacy! UCI MIND is honored to partner with Shriver and her organization, the Women’s Alzheimer’s Movement (WAM), to unravel why 2 out of every 3 people with Alzheimer’s are women. Thanks to Shriver and other local philanthropists, the UCI MIND-WAM Women’s Initiative has now awarded $400,000 to UCI scientists for sex and gender disparities research. Variety: “So much of my work is about awareness, prevention, funding of research and trying to educate people about something they think they don’t have to worry…

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Oct 15
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Drs. Xu and Cotman receive $3M from NIH to map aging-associated brain changes

By Carousel Slider, Commentary, In the News, UCI MIND

Irvine, Calif. – October 15, 2020 – The National Institutes of Health has awarded a team of researchers, led by the University of California, Irvine’s Xiangmin Xu, PhD, a five-year, $3 million grant for a project titled, “Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus.” Now, as part of the 4D Nucleome consortium, Xu, a professor of anatomy and neurobiology and director of the Center for Neural Circuit Mapping at the UCI School of Medicine, together with MPIs, Carl Wayne Cotman, PhD, a professor of neurology and founding director of the UCI Institute for Brain Aging and Dementia,…

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Oct 12
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Mark your calendar for upcoming virtual events!

By Commentary, Community Events, UCI MIND

Mark your calendar for upcoming virtual events! Wellness Wednesday: Healthy Brain Aging Live Q&A with Joshua Grill, PhD and Ruth Benca, MD, PhD moderated by Debra Hill, MD, UCI School of Medicine Alumni Board Wednesday, October 28, 2020 | 7:00 – 8:00 pm PDT Register online: Click here How does heart health impact the brain? Live Q&A with Daniel Nation, PhD Friday, November 6, 2020 | *1:00 – 1:30 pm PST* Tune in on Facebook: facebook.com/ucirvinemind Caring for the Caregiver Live Q&A panel on the unique challenges facing dementia caregivers during the COVID-19 pandemic, moderated by Joshua Grill, PhD Tuesday, November 10, 2020 | 4:00 –…

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Oct 09
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How CRISPR is revolutionizing our study of complex diseases, like Alzheimer’s

By Commentary, In the News, UCI MIND

Contributed by Jean Paul Chadarevian & Amanda McQuade Dr. Emmanuelle Charpentier and Dr. Jennifer A. Doudna make history as the first all-female team to be awarded the Nobel Prize in Chemistry for their pioneering discovery of CRISPR-Cas9, a highly specific and efficient genome editing technology. Charpentier, Director at the Max Planck Institute for Infection Biology in Berlin, and Doudna, biochemist at the UC Berkeley, first described the CRISPR-Cas9 system in their 2012 publication in Science. CRISPR, or Clustered Regularly Interspaced Short Palindromic Repeats, was first observed in the bacterial immune system. Like us, bacteria are prone to viral infections; however,…

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Oct 07
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Wellness Wednesday: Healthy Brain Aging

By Commentary, Community Events, Event Slider, UCI MIND

Wellness Wednesday: Healthy Brain Aging October 28, 2020 7 – 8 p.m. PDT Via Zoom Join us for a live presentation and Q&A with UCI School of Medicine faculty and Alzheimer’s researchers, Joshua Grill, Ph.D., Director of UCI MIND, and Ruth Benca, M.D., Ph.D., Director of UCI Sleep Center. Learn about risk factors for Alzheimer’s disease and lifestyle strategies for maintaining a healthy brain as you age. The program will be moderated by Debra A. Hill ’78, M.D., Co-President of the UCI School of Medicine Alumni Chapter.   Joshua Grill, Ph.D. Director of the Institute for Memory Impairments and Neurological Disorders (UCI…

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Oct 07
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Helping People With Dementia Exercise Their Right to Vote

By Commentary, COVID-19, In the News, UCI MIND

The novel coronavirus pandemic and a US Postal Service slowdown may not be the only hurdles facing people with dementia who want to vote in the 2020 general election. Nearly 6 million people in the US have some form of the condition, the US Centers for Disease Control and Prevention estimates, and they represent almost 2.5% of the 253.8 million US residents who are of voting age. The oldest voters, those aged 60 years or older, are more likely to vote than younger age groups, according to the United States Elections Project; the lion’s share of people with dementia fall…

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Oct 05
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UC Irvine partners with O.C. businesses to develop safe reopening protocols

By Carousel Slider, Community Events, In the News, UCI MIND

UC Irvine is providing consulting services to private businesses to develop rules and procedures to keep employees and customers safe from COVID-19 as the economy starts to open up. “As the only program in public health in Orange County, we have an obligation to assist our community,” UCI professor Karen Edwards said in a press release. “I think there’s a gap in this area for us to step up and offer these types of services. This has the potential to have a major positive impact.” Orange County was on track to move into the state’s less restrictive orange tier until…

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Oct 05
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This Week is FTD Awareness Week! Learn about AD-Related Dementias

By Commentary, In the News, UCI MIND

Contributed by S. Ahmad Sajjadi, MD, PhD   Alzheimer’s disease is and will likely remain the commonest cause of dementia. A less well-known fact, however, is that there are also other dementia causing pathologies that are commonly referred to as Alzheimer’s disease related dementia (ADRD). While the scientific community is warming up to the idea that it should consider these other causes in all dementia related research, there is a pressing need for the wider community to be informed about them. These alternative causes of dementia are often age dependent. In people who are younger than 65 years old, a…

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